Treatments For Severe Acne

Sephora customers often prefer the following products when searching for Treatments For Severe Acne.

If you have severe acne, you may be experiencing a great deal of frustration. There are many different types of treatments for severe acne that can help you get clear skin once and for all.

Peter Thomas RothPotent-C™ Niacinamide Discoloration Treatment

ITEM: 2743730

Size: 1.7 oz / 50 ml

224 Reviews

$65.00

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I have a lot of discolorations from my acnes and this is helping. I do see them lightening up a bit so we'll see how this goes but so far so good. ...Its good for evening redness/no for acne scars...If your concerns are lightening up acne scarring or sever huperpigmentation id look elsewhere tho as i feel maybe this may not be strong enough to actually do that

The OrdinaryArgireline Solution 10% Serum for Facial Wrinkles

ITEM: 2210714

Size: 1 oz/ 30 mL

395 Reviews

$9.70

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Been using for a while, doesn’t really do much for my wrinkles and gives me cystic acne. Normally I don’t have cystic acne ever...I love this treatment it started to work instantly after application I would highly recommend this and the texture is so light you can combine it with other treatments

Dr. Dennis Gross SkincareAlpha Beta® Extra Strength Daily Peel Pads

ITEM: 1491497

Size: 60 Treatments

7.7K Reviews

$153.00

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After having a baby I started breaking out so bad, I had big and small acne. I always had acne but not as much as after gloving birth. ...It is a little pricy and I didn't have bad acne to begin with. I don't know if it is worth the price, maybe if you suffer from sever acne scars it might be helpful.

What it is: A two-step AHA/BHA peel pad pre-dosed with seven acids and 12 antioxidants to clear the complexion, reduce the look of wrinkles, and visibly improve skin tone and texture.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Uneven Texture, and Acne and Blemishes

Formulation: Wipes

Highlighted Ingredients:
- Glycolic Acid (AHA) and Mandelic Acid (AHA): Visibly reduces lines and wrinkles and balances skin.
- Salicylic Acid (BHA): Clears clogged pores.
- Resveratrol and Green Tea Extract: Supports skin cell lifespan and protects against free radicals.

Ingredient Callouts: This product is vegan and cruelty-free.

What Else You Need t

Paula's ChoiceClinical PRO Retinaldehyde Dual-Retinoid Treatment for Clear, Luminous Skin

ITEM: 2784890

Size: 1 oz / 30 mL

687 Reviews

$68.00

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Paula’s Choice CLINICAL Pro Retinaldehyde Dual-Retinoid Treatment truly did wonders for my skin. If you have uneven skin texture, post acne scars, or acne in general, this product is for you. ...love this treatment!...This treatment is great. I have acne prone skin and love using retinol treatments on my face.

What it is: A high-potency dual retinoid formula delivers derm-level results for clear, luminous skin with minimal chance of irritation—no prescription needed.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Uneven Texture, and Acne and Blemishes

Formulation: Cream

Highlighted Ingredients:
- Retinaldehyde: Calcium encapsulated for advanced results with minimized irritation.

- Adapinoid: An oil-soluble retinoid that promotes clear-looking skin.

- Pomegranate Peel Extract: Supports healthy collagen production and soothes.

Paula's ChoiceCLINICAL Anti-Aging 1% Retinol Treatment

ITEM: 2421295

Size: 1 oz/ 30 mL

692 Reviews

$65.00

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It didn’t break me out or have any bad reactions. Also, it didn’t dry me out over if you’re looking for a good retinol treatment this maybe the one for you ....With acne prone skin and acne scars, I am always looking for ways to help reduce the visibility of scars.

What it is: An advanced 1% retinol formula with skin-supportive peptides and vitamin C, smooths wrinkles and firms skin to reduce visible signs of aging.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Pores, and Loss of Firmness and Elasticity

Formulation: Lightweight Cream

Highlighted Ingredients:
- Retinol (Vitamin A) 1%: A potent, slow-release concentration that visibly improves signs of aging.

Sunday RileyAll About Acne Breakout + Blackhead Set

ITEM: 2377653

29 Reviews

$95.00

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Amazing, cleared my acne after only 2 weeks of using!!...I haven't used the sulfur acne treatment mask much mostly because it smells really strong but when I have it has been great.

What it is: A quick and complete routine that targets blemishes and blackheads with pore-clearing salicylic acid, sulfur, retinoids, and lactic acid.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Pores, Redness, and Acne and Blemishes

Highlighted Ingredients:
- Retinoid Complex: Minimizes the look of pores, addresses visible signs of aging, and helps skin appear clear and smooth.
- Salicylic and Lactic Acids: Salicylic acid dissolves sebum buildup, minimizing the appearance of pores and combating breakouts, while lactic acid visibly clarifies the skin, exfoliating away pore-clogging debris that can lead to acne and blackheads.

Luna DailyThe Repair Treatment – For Scars & Hyperpigmentation - Best For Acne and Post-Surgery - Silicone Free

ITEM: 2766400

Size: 1.69 oz / 50 ml

101 Reviews

$56.00

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It’s different than any other stretch mark treatment I’ve tried. I didn’t notice much benefit yet on acne scar, cut scar and surgery scars. ...Luna daily repair treatment came in handy when I needed the extra care for my stretch marks on my belly and the acne scars .

What it is: A silky, serum-gel that supports the natural skin barrier and promotes skin recovery.

Skin Type: Normal, Dry, Combination, and Oily

Highlighted Ingredients:
- Gransense®: Bio-based silicone alternative to support natural collagen and cell renewal.

- Kahai Oil®: Clinically shown to visibly reduce scarring and discoloration.

- Arnica Extract: Reduces redness and soothes skin.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free, and comes in recyclable packaging.

What Else You Need to Know: Clinically tested daily scar treatment to

The INKEY ListC-50 Blemish Night Treatment

ITEM: 2425080

Size: 1 oz/ 30 mL

79 Reviews

$17.00

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I like this product because it’s the easiest to apply acne treatment that I’ve ever used - rather than being a spot treatment that you have to then try to apply moisturizer on top of without rubbing it off, this is both acne treatment and moisturizer, so you apply it as the final step of your nightly routine. ...Acne treatment must have...If you struggle with constant acne, get this.

What it is: An overnight treatment, with its powerful combination of vitamins C and E, that helps reduce bacteria count on your skin to prevent and reduce the appearance of blemishes.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Pores, Uneven Texture, and Acne and Blemishes

Highlighted Ingredients:
- 5% STAY®-C 50: Prevents and reduces the look of blemishes and breakouts.
- 2% Salicylic Acid: Gently exfoliates, removing dead skin cells and unclogging the appearance of pores.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

What Else You Need to Know: This is a stable Vitamin C derivative that visibly brightens and evens skin tone.

CaudalieVinopure Color Correcting Spot Solution with Salicylic Acid

ITEM: 2671766

Size: .5 oz / 15 ml

249 Reviews

$25.00

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They are small and occasionally I get a medium or big one. I used this spot treatment on my acnes of various stages. Overall it helps shrink the size of the acnes and helps eliminate them quicker. ...My favourite acne/blemish treatment...This is now my favourite acne/blemish spot treatment. It takes away pimples within a day or 2.

What it is: A targeted cream for acne spots that visibly reduces breakout size in as little as one hour.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Pores, Acne and Blemishes, and Oiliness

Highlighted Ingredients:
- 100% Natural Salicylic Acid: Naturally exfoliates and visibly refines skin texture.
- Niacinamide: Minimizes the appearance of pores.
- Tea Tree: Purifies the skin.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

What Else You Need to Know: A natural and non-drying purifying cream that targets acne spots fast and reduce breakout size. Use this leave-on cream under makeup to color correct redness with natural green pigments.

The INKEY ListMandelic Acid Treatment

ITEM: 2530731

Size: 0.5 oz/ 15 mL

291 Reviews

$13.00

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This is the best ingredient The Inkey List has ever made, my acne fades so much quicker since using this! And I am noticing my post acne redness is not as severe, seriously but this!...my acne scars are (almost) gone 🙀...Okay so i bought this after some really bad cystic acne cleared up because the scarring was Really bad.

What it is: A clinically shown, fast-acting, targeted formula that reduces the look of hyperpigmentation and discoloration left behind by blemishes.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dark Spots and Acne and Blemishes

Highlighted Ingredients:
- Mandelic Acid 10%: Reduces the appearance of dark spots, hyperpigmentation, and post-blemish marks.
- Glycerin 2%: Hydrates skin and draws in moisture.
- Encapsulated Retinol 0.1%: Helps fade the appearance of dark spots and discoloration.

Ingredient Callouts: This product is vegan, cruelty-free, and comes in recyclable packaging.