Best Acne Spot Treatments

Sephora customers often prefer the following products when searching for Best Acne Spot Treatments.

Acne can be a frustrating and confidence-denting skin concern that many of us have experienced at some point. When those pesky pimples pop up, it's important to have effective spot treatments on hand to help combat them. Whether you're dealing with occasional breakouts or persistent blemishes, these acne spot treatments are here to save the day. These targeted solutions are designed to help reduce the appearance of acne, minimize redness, and promote clearer-looking skin.

$30.00

I am glad I finally decided to buy this acne spot treatment . It smells bad but the scent isn’t overwhelming. ...Very effective acne treatment, helps the skin to regenerate and eradicate the acnes more quickly....Very effective acne treatment

What it is: An acne treatment gel with 1.5% Salicylic Acid for on-the-spot, targeted treatment––wherever you go.


Skin Type: Normal, Dry, and Oily


Skincare Concerns: Acne and Blemishes, Redness, and Oiliness


Formulation: Gel


Highlighted Ingredients:

- Saw Palmetto: Helps control oil, reduce shine, and prevent breakouts.


What Else You Need to Know: This blemish-fighting formula with saw palmetto and 1.5 percent salicylic acid helps eliminate excess oil that can lead to break outs.

DermalogicaRetinol Clearing Oil

ITEM: 2356707

Size: 1 oz / 30 mL

27 Reviews

$124.00

Works very well - usually only need 4 drops to cover my whole face and I notice a huge difference in my skin when I wake up in the morning! Good to use for spot treatment as well....Best thing I’ve bought all year...It’s been 5 days since I started using this product, my acne has cleared up with only one small new spot appearing and I expect it will be gone by morning

What it is: A high-performance night oil that combines retinol and salicylic acid for the first time to help clear breakouts and visible signs of premature aging.

Skin Type: Normal, Combination, and Oily

Skincare Concerns: Fine lines and wrinkles, acne and blemishes, and uneven texture.

Formulation: Oil

Highlighted Ingredients:
- Retinol: Supports natural skin renewal to diminish the appearance of fine lines, wrinkles, and uneven skin tone.
- Salicylic Acid: Supports natural exfoliation to help clear clogged follicles and smooth dullness that contribute to visible skin aging.

The INKEY ListMandelic Acid Treatment

ITEM: 2568905

Size: 0.5 oz/ 15 mL

281 Reviews

$17.50

Definitely lightened up the dark spots and great for acne spot treatment. Overall great product for troubled skin....This is by far the BEST spot treatment I have ever used. I’ve been struggling with stubborn acne and this helps make a noticeable difference overnight.

What it is: A fast-acting targeted treatment that is clinically shown to reduce the look of hyperpigmentation and discoloration leftover from acne spots and blemishes.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dark Spots and Acne and Blemishes

Highlighted Ingredients:
- 10% Mandelic Acid: Reduces the look of dark spots, hyperpigmentation, and post-acne marks.
- 2% Glycerin: Hydrates skin and draws in moisture.
- 0.1% Encapsulated Retinol: Supports increased cell turnover and fades the look of dark spots and discoloration.

Ingredient Callouts: This product is vegan, cruelty-free, and comes in recyclable packaging.

$149.00

Unlike some other retinoid treatments, the Equilibrium Resurfacing Retinoid Treatment does not cause irritation or redness, making it suitable for most sensitive skin types.I have noticed a significant improvement in the overall texture and tone of my skin. ...Love using this treatment and I’m truly amazed by the results. This retinol treatment helps to reduce dark spots and fine line and wrinkles.

What it is: A lightweight resurfacing treatment that boosts clarity and helps visibly even skin texture and tone for more balanced skin with a healthy glow.

Highlighted Ingredients:
- Retinoid, Hexylresorcinol, and Niacinamide: A clinically backed blend that visibly reduces fine lines and wrinkles and diminishes the appearance of dark spots and hyperpigmentation while being gentle to skin.

Ingredient Callouts: Free of parabens and mineral oil. It is also cruelty-free.

What Else You Need to Know: This fast-absorbing treatment is formulated with a blend of a retinoid, hexylresorcinol, and niacinamide to visibly reduce fine lines and wrinkles and diminish the appearance of dark spots and hyperpigmentation. The formula is ef

MuradRapid Relief Acne Spot Treatment

ITEM: 1968320

Size: 0.5 oz/ 15 mL

638 Reviews

$35.00

Best spot treatment...This is the best spot treatment I’ve ever tried. I saw a difference in my spots very quickly and they didn’t come back. ...This is a lifer saver spot treatment. I have been struggling to mask acne for 2 months and tried other expensive spot treatments but didn't work.

Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A maximum strength two percent salicylic acid gel formula that reduces blemish size and redness in as little as four hours.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This maximum strength formula contains salicylic acid to exfoliate, clear pores, and smooth skin. Inspired by pine and thyme extracts, a patented complex fights irritants while preserving skin’s healthy balance. The clear gel formula works well under makeup without pilling or peeling to treat blemishes while concealing.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

$57.00

I love the the Pre-Show Glow Instant Retexturizing Treatment. I used this product twice a week and can see an improvement in my skin’s dark spots and vibrance. ...The product leaves your skin feeling silky smooth! I have acne prone skin with dark spots and this seems to have improved the spots thus far!

What it is: This one minute 10% AHA treatment clarifies, purifies, brightens and smooths skin by gently clearing dull surface cells to even texture over time.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dark Spots, Dullness, and Uneven Texture


Formulation: Liquid

$79.00

This overnight treatment is a game changer!...I’m so impressed by this overnight treatment. I immediately woke up to brighter, hydrated and a more even skin tone. ...Great overnight treatment for dark spots!...I would definitely recommend it to anyone who wants to brighten dark spots!

What it is: A visibly brightening oil infused with niacinamide and vitamin C to recharge skin’s visible radiance while you sleep—for a glowing look by morning.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Lightweight Oil

Highlighted Ingredients:
- Vita-Charge™ Brightening Complex: Visibly brightens skin and improves dark spots.
- Lactic and Mandelic Acids: Visibly even skin tone and texture.
- Seaberry, Turmeric, and Ginseng: Replenish and nourish skin.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone,

$89.00

This makes it a fantastic option for those with sensitive skin or anyone new to retinol treatments. Overall, the CLINICAL 0.3% Retinol + 2% Bakuchiol Treatment has exceeded my expectations. ...Best retinol in the market!...I also noticed my acne scars looked brighter than before and my pores look visibly smaller which is a huge deal for me!

What it is: A retinol-, bakuchiol-, and peptide-powered formula that supports skin's natural elasticity, reduces the look of lines and wrinkles, and addresses loss of firmness.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Pores, and Loss of Firmness and Elasticity

Formulation: Lightweight Cream

Highlighted Ingredients:
- Retinol 0.3%: Reduces the look of fine lines and wrinkles.
- Bakuchiol 2%: Amplifies retinol's visible effect on skin.
- Peptides: Support natural elasticity and visibly firm skin.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal ta

$57.00

Dennis Gross’s Advanced Retinol + Ferulic Perfectly Dosed Retinol Treatment is a skincare game-changer. LAfter four weeks, I noticed reduced dark spots, smoother texture, and increased radiance. ...Wow! This retinol treatment is a game-changer. My fine lines and dark spots are visibly reduced, and my skin texture is smoother.

What it is: A targeted, overnight peel treatment to reduce fine lines, improve uneven tone and texture, and restore hydration for a radiant, healthy-looking complexion.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dark Spots, Fine Lines and Wrinkles, and Uneven Texture


Highlighted Ingredients:

- Retinol: A vitamin A derivative that supports collagen production while visibly reversing signs of photo-aging, improving fine lines and wrinkles, addressing UV-induced free-radical damage, reducing blemish-causing sebum, and fading dark spots.

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