Overnight Pimple Treatments

Sephora customers often prefer the following products when searching for Overnight Pimple Treatments.

Combat pesky pimples while you catch some Z's with our selection of overnight pimple treatments. Say goodbye to blemishes and wake up to clearer, healthier-looking skin with these targeted solutions designed to work their magic while you sleep. From potent spot treatments to gentle overnight serums, we have everything you need to tackle breakouts and achieve a smoother complexion by morning. Discover the power of overnight skincare and bid farewell to unwanted visitors on your skin.

MuradRapid Relief Acne Spot Treatment

ITEM: 1933100

Size: 0.5 oz/ 15 mL

638 Reviews

$26.00

Have tried everything from drying lotion to sulfur treatments, this flattens out my pimple within 24 hours....This spot treatment eliminates my pimples overnight. This is simply amazing!

What it is: A maximum-strength, two-percent-salicylic-acid gel that soothes the skin, targets acne, and visibly reduces blemish size and redness in as little as four hours.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Acne and Blemishes and Oiliness

Formulation: Gel

Highlighted Ingredients:
- Salicylic Acid 2%: Penetrates pores to exfoliate and visibly smooth the skin.
- Oat Extract: Soothes the skin and reduces the look of redness.
- Witch Hazel: Absorbs excess oil and visibly tightens pores.

Ingredient Callouts: Free of parabens, formaldehydes, phthalates, mineral oil, oxybenzone, and sulfates SLS & SLES. It is also vegan, gluten-free, and cruelty-free.

$46.00

The POREfessional Shrink Wrap Overnight AHA+PHA Pore Treatment is the perfect overnight treatment I have tried so far. ...Unlike many overnight treatments that feel heavy or greasy, The POREfessional absorbs quickly, leaving behind a lightweight, breathable veil.

What it is: An overnight pore treatment packed with a balanced blend of acids to shrink the look of pores.


Skin Type: Normal, Dry, Combination, and Oily


Highlighted Ingredients:
- Glycolic Acid and Lactic Acid (AHAs): Visibly tighten pores and reveal brighter-looking skin.

- Gluconolactone (PHA): Visibly retexturizes skin.

- Niacinamide: Minimizes and refines the look of pores.


Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthe

$18.00

Finally a spot treatment product that works...I have been looking for an overnight pimple treatment for awhile that is both a good price and actually works. ...I’ve tried a lot of these overnight pimple healers and hands down this is my favorite.

What it is: A fast-acting blemish spot treatment that zaps pimples overnight with zero irritation and helps brighten the look of spots from past breakouts.

Skin Type:
Normal, Dry, Combination, and Oily

Skincare Concerns: Acne/Blemishes and Oiliness

Highlighted Ingredients:
- Clay and Sulfur: Absorb excess oil and balance sebum production.
- Willow Bark: Nature's alternative to salicylic acid, it helps calm breakouts and clear pores.
- Azelaic Acid: Helps prevent spots left by past blemishes.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

$9.00

I noticed that if I leave the pimple patches on overnight my pimple clears up pretty quickly!...simple and super effective pimple patches!...They sit on my face & don't budge & I can leave them overnight for treatment. I prefer to use patches overnight but I've tried on stubborn spots during the day & was really pleased with how well these work.

What it is: The only patch clinically proven to visibly reduce breakouts in 4 hours*, packed with a powerful breakout-fighting blend including Salicylic Acid.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Redness, Acne and Blemishes, and Oiliness


Formulation: Mask


Highlighted Ingredients:
- 99% Hydrocolloid: Extracts gunk, flattens imperfections’ appearance, and creates a protective seal.

- 0.4% Salicylic Acid: Exfoliates to unclog pores and visibly reduce blemishes

$39.00

This overnight treatment oil helps reduce the look of fine lines, wrinkles, uneven tone and texture. ...I really like this retin oil treatment to use overnight! It goes on my skin very smooth and feels great and hydrating.

What it is: An overnight oil powered by a custom-blended two percent vegan retinol that reduces the look of fine lines, wrinkles, uneven tone, and texture.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dullness, and Uneven Texture

Formulation: Oil

Highlighted Ingredients:
- Vegan Retinol 2%: Smooths the look of fine lines and wrinkles.
- Sunflower, Soybean, Chia, and Rosehip Oils: Leave skin feeling nourished, hydrated, and supple.
- Rice Bran Extract: Moisturizes and visibly reduces uneven tone and texture.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free, and comes in recyclable packaging.

$20.00

I truly love this product helps my acne disappear but I will say it’s very drying . I usually do a overnight spot treatment and by morning my pimples will be gone but it does leave a red dot but I don’t mind as long as the pimple is gone...i loooove this. i use it as a spot treatment overnight and every time i see a huge difference in the pimple. it is usually flat or nearly gone after use. one of the best spot treatments i’ve used. a little goes a long way however so i find I only need a thin layer on my trouble spots !

What it is: A spot treatment containing sulfur, niacinamide, tea tree oil, and manuka oil to diminish the appearance of breakouts and cleanse skin for a smooth, visibly clear complexion.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Redness, Blemishes, and Oiliness

Formulation: Mask

Highlighted Ingredients:
- Sulfur: Diminishes the appearance of blemishes and addresses the formation of new ones.
- Bentonite: Absorbs excess oil, removes impurities, and diminishes the appearance of pores.
- Niacinamide 4%: Reduces the appearance of blemishes and surface redness and visibly improves congested skin.

$24.00

I have used SO many different spot treatments, but this one literally gave me results in one night! ...I’ve always been a fan of Paula’s choice and is excited to say this skin clearing treatment works well too! It takes a week or so to see some results of pimple fading.

What it is: A clinically demonstrated, benzoyl-peroxide-powered formula that fights and prevents the appearance of breakouts, absorbs excess oil, and visibly calms redness.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Pores, Acne and Blemishes, and Oiliness

Formulation: Lightweight Gel

Highlighted Ingredients:
- Benzoyl Peroxide 2.5%: Targets acne-causing bacteria on contact.
- Bisabolol: Reduces visible signs of sensitivity and irritation to minimize dryness and flaking.
- Allantoin: Calms and soothes the skin while visibly minimizing redness.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, and mineral oil.

Mario BadescuDrying Lotion

Size: 1 oz/ 29 mL·ITEM: 2387983

Type: Travel-Friendly Plastic Bottle

446 Reviews

$18.00

Good spot treatment for acne prone normal/dry skin...Really great for spot treatments! Gets zits down to a manageable size overnight....Overnight Acne Fix...Only pimple treatment that truly zaps my blemishes overnight.

What it is: An original, award-winning solution that dries up surface blemishes overnight.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Acne and Blemishes

Formulation: Lightweight Liquid

Highlighted Ingredients:
- Salicylic Acid: Exfoliates to help shed pore-clogging dead skin cells.
- Sulfur: Cleanses pores and absorbs excess oil.
- Calamine: Delivers a cooling, soothing effect.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, and triclocarban, and contains less than one percent of synthetic fragrances.

$20.00

Dried out the pimples...This product is easy to use and apply. It dries the pimple in 2 days completely. I used it overnight and it helped with an inflamed pimple and after 2 days it was gone. ...These were literally so well dissolving pimples overnight, and got rid of a pimple that was forming under my skin overnight.

What it is: A patented, acne-fighting patch designed to tackle below-the-surface breakouts before they appear.

Skin Type:
Normal, Dry, Combination, and Oily

Skincare Concerns: Redness and Acne and Blemishes

Formulation: Mask

Highlighted Ingredients:
- Salicylic Acid: Penetrates pores to target blemishes and blackheads.
- Niacinamide: Fades dark spots and supports elasticity and barrier function.
- Succinic Acid: Supports balanced sebum production, addressing shine and excess oil.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains

$30.00

Sometimes I would notice a slight diminishment in the size and shape of a zit after an overnight pimple patch, and sometimes there was no change at all. ...I’ve tried many (too many) pimple treatments and this is definitely one of the better ones.

What it is: An invisible liquid pimple patch formulated with two percent salicylic acid to visibly reduce pimple color and size and fade post-blemish marks.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dark Spots and Acne and Blemishes

Highlighted Ingredients:
- 2% Salicylic Acid: Rapidly clears acne while exfoliating and refining skin texture.
- 4% Niacinamide: Visibly fades post-blemish marks and discoloration.
- 0.2% Licorice Root: Soothes and calms visible redness.

Ingredient Callouts: This product is vegan and comes in recyclable packaging.

What Else You Need to Know: Formulated with medicated salicylic acid, niacinamide, and licorice root, this formula uses liq

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